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Krankenhaus vs. Klinik

In German, both Krankenhaus and Klinik translate to hospital or clinic. While they are often used interchangeably in everyday speech, they carry different nuances regarding size, specialization, and affiliation.

Krankenhaus

A1
This is the most general and common word for a hospital. Literally meaning sick house, a Krankenhaus is typically a large, often public, facility that provides a broad range of medical treatments for various illnesses and emergencies. It is the default term used in everyday conversation.
Nach dem Autounfall wurde sie sofort ins Krankenhaus gebracht.
(After the car accident, she was immediately taken to the hospital.)
Mein Onkel liegt seit letzter Woche im Krankenhaus.
(My uncle has been in the hospital since last week.)
Das städtische Krankenhaus hat eine sehr gute Notaufnahme.
(The municipal hospital has a very good emergency room.)
Die Besuchszeiten im Krankenhaus sind von 14 bis 18 Uhr.
(The visiting hours at the hospital are from 2 PM to 6 PM.)

Klinik

B1
This term also means hospital but often implies a level of specialization. A Klinik can be a smaller, often private institution focusing on a specific field (e.g., an eye clinic), a department within a larger hospital, or a university-affiliated hospital (Universitätsklinik) involved in research and teaching. It is also the standard term for rehabilitation centers (Reha-Klinik).
Er ist Chefarzt in einer berühmten Herzklinik.
(He is the chief physician at a famous heart clinic.)
Die Studenten der Medizin machen ihr Praktikum in der Universitätsklinik.
(The medical students are doing their internship at the university hospital.)
Nach seiner Operation muss er für sechs Wochen in eine Reha-Klinik.
(After his surgery, he has to go to a rehabilitation clinic for six weeks.)
Diese Privatklinik ist auf Sportverletzungen spezialisiert.
(This private clinic specializes in sports injuries.)
Meine Tante arbeitet in der Augenklinik.
(My aunt works in the eye clinic.)

Summary

In essence, Krankenhaus is the general, all-purpose word for a hospital. Klinik often points to a more specialized facility, a university hospital, a private institution, or a rehabilitation center. However, it's important to note that many large hospitals now officially call themselves Klinik or Klinikum for marketing or branding reasons, making the terms increasingly synonymous in official names, even if the nuanced difference remains in common perception.